Due to their small size and high surface area, nanomaterials can demonstrate unique chemical and physical properties not seen in their bulk analogues. Their use is increasingly expanding from niche to widespread commercial applications. For instance, if you are wearing socks with “silver” technology for extra freshness, you are using a nanomaterial. The properties that give nanomaterials their unique commercial applications are feared to present new or increased toxicological impacts. Nanomaterials have been found in organs and cells inaccessible to the same substance in either bulk or solution form. These concerns have led to calls for greater regulatory control of these substances.