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29 substances added to the Highly Mutagenic Chemical Substances

MHLW designated a list of 29 substances to be included in the highly mutagenic chemical substances list under ISHA. Companies manufacturing or handling the listed substances are subjected to regulation “Guidelines for preventing health hazards caused by mutagenic chemical substances” which requires the company to take several measures to protect workers health.

Highly Mutagenic Chemical Substances List can be accessed at

Yordas Group can support you at every stage towards successful notification in Asia Pacific, from providing up-to-date information and identifying your regulatory obligations, to substance characterisation, commissioning of testing, risk assessment and submission of notifications. We provide in-country representation through our network of local partners. For more information on how these latest regulatory updates may affect your business, call our expert team on +44 (0)1524 510278 or email

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